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Rapid Identification of Key Copy Number Alterations in B- and T-Cell Acute Lymphoblastic Leukemia by Digital Multiplex Ligation-Dependent Probe Amplification

Recurrent clonal genetic alterations are the hallmark of Acute Lymphoblastic Leukemia (ALL) and govern the risk stratification, response to treatment and clinical outcome. In this retrospective study conducted on ALL patient samples, the purpose was to estimate the copy number alterations (CNAs) in...

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Detalles Bibliográficos
Autores principales: Thakral, Deepshi, Kaur, Gurvinder, Gupta, Ritu, Benard-Slagter, Anne, Savola, Suvi, Kumar, Indresh, Anand, Rajni, Rani, Lata, Verma, Pramod, Joshi, Sangeeta, Kumar, Lalit, Sharma, Atul, Bakhshi, Sameer, Seth, Rachna, Singh, Vivek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753626/
https://www.ncbi.nlm.nih.gov/pubmed/31572674
http://dx.doi.org/10.3389/fonc.2019.00871