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Factors Involved in Relapse of Multiple Sclerosis

Multiple sclerosis (MS), a chronic autoimmune disorder, affects the central nervous system (CNS). It affects the brain, spinal cord, and optic nerve, leading to problems with vision, balance, muscle control, and other basic bodily functions. MS relapse (MSR) involves an acute inflammatory demyelinat...

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Autor principal: Kamel, Fatemah Omar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753697/
https://www.ncbi.nlm.nih.gov/pubmed/31548920
http://dx.doi.org/10.4103/JMAU.JMAU_59_18
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author Kamel, Fatemah Omar
author_facet Kamel, Fatemah Omar
author_sort Kamel, Fatemah Omar
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description Multiple sclerosis (MS), a chronic autoimmune disorder, affects the central nervous system (CNS). It affects the brain, spinal cord, and optic nerve, leading to problems with vision, balance, muscle control, and other basic bodily functions. MS relapse (MSR) involves an acute inflammatory demyelinating reaction within the CNS. This review focuses on the main factors involved in MSR based on a detailed literature search. Evidence suggests that MSR is influenced by age, sex, pregnancy, serum levels of Vitamin D, interactions between genetic and environmental factors, and infectious diseases. Many of these factors are modifiable and require the attention of patients and health-care providers if favorable outcomes are to be realized. Identification of MSR risk factors can help in the development of therapies that could be used to manage MS and MSR.
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spelling pubmed-67536972019-09-23 Factors Involved in Relapse of Multiple Sclerosis Kamel, Fatemah Omar J Microsc Ultrastruct Review Article Multiple sclerosis (MS), a chronic autoimmune disorder, affects the central nervous system (CNS). It affects the brain, spinal cord, and optic nerve, leading to problems with vision, balance, muscle control, and other basic bodily functions. MS relapse (MSR) involves an acute inflammatory demyelinating reaction within the CNS. This review focuses on the main factors involved in MSR based on a detailed literature search. Evidence suggests that MSR is influenced by age, sex, pregnancy, serum levels of Vitamin D, interactions between genetic and environmental factors, and infectious diseases. Many of these factors are modifiable and require the attention of patients and health-care providers if favorable outcomes are to be realized. Identification of MSR risk factors can help in the development of therapies that could be used to manage MS and MSR. Wolters Kluwer - Medknow 2019 /pmc/articles/PMC6753697/ /pubmed/31548920 http://dx.doi.org/10.4103/JMAU.JMAU_59_18 Text en Copyright: © 2019 Journal of Microscopy and Ultrastructure http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Kamel, Fatemah Omar
Factors Involved in Relapse of Multiple Sclerosis
title Factors Involved in Relapse of Multiple Sclerosis
title_full Factors Involved in Relapse of Multiple Sclerosis
title_fullStr Factors Involved in Relapse of Multiple Sclerosis
title_full_unstemmed Factors Involved in Relapse of Multiple Sclerosis
title_short Factors Involved in Relapse of Multiple Sclerosis
title_sort factors involved in relapse of multiple sclerosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753697/
https://www.ncbi.nlm.nih.gov/pubmed/31548920
http://dx.doi.org/10.4103/JMAU.JMAU_59_18
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