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Prenatal and postnatal echocardiography in NT fetuses with normal karyotype

INTRODUCTION: Targeted fetus echocardiography at midpregnancy can detect major defects in major cardiovascular organs. The present study aimed to evaluate prenatal and postnatal echocardiography in fetuses with increased nuchal translucency (NT) with normal karyotype. METHODS: In this retrospective...

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Autores principales: Emami-Moghaddam, Abdolrahman, Barati, Mojgan, Amirpour, Razie, Shojaei, Kobra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753816/
https://www.ncbi.nlm.nih.gov/pubmed/31548952
http://dx.doi.org/10.4103/jfmpc.jfmpc_395_19
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author Emami-Moghaddam, Abdolrahman
Barati, Mojgan
Amirpour, Razie
Shojaei, Kobra
author_facet Emami-Moghaddam, Abdolrahman
Barati, Mojgan
Amirpour, Razie
Shojaei, Kobra
author_sort Emami-Moghaddam, Abdolrahman
collection PubMed
description INTRODUCTION: Targeted fetus echocardiography at midpregnancy can detect major defects in major cardiovascular organs. The present study aimed to evaluate prenatal and postnatal echocardiography in fetuses with increased nuchal translucency (NT) with normal karyotype. METHODS: In this retrospective study, data on the screening of fetuses in pregnant women between 2014 and 2015 were evaluated. The fetuses at the gestational age were 14–11 weeks, and NT ≥ 95 percentile (or 3 mm). For all fetuses with increased NT, follow-up anomaly scan was performed at 18–22 weeks of pregnancy, while fetal echocardiography was performed at weeks 16–19 of pregnancy. The results were analyzed by Statistical Package for the Social Sciences (version 22) and the level of significance was less than 0.05. RESULTS: A total of 26.27% of the fetuses were diagnosed with prenatal heart defects and confirmed after birth. The strongest relationship was observed between increased NT and the diagnosis of prenatal heart defects at 2.5–5.3 mm. The increased NT was higher in younger mothers. Moreover, increased NT was higher in mothers with less body mass index. CONCLUSION: By measuring NT in the 11–13 weeks of pregnancy and considering the risk factors, it is possible to evaluate the probability of cardiac abnormalities in the fetus and perform the necessary diagnostic evaluations for high-risk cases.
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spelling pubmed-67538162019-09-23 Prenatal and postnatal echocardiography in NT fetuses with normal karyotype Emami-Moghaddam, Abdolrahman Barati, Mojgan Amirpour, Razie Shojaei, Kobra J Family Med Prim Care Original Article INTRODUCTION: Targeted fetus echocardiography at midpregnancy can detect major defects in major cardiovascular organs. The present study aimed to evaluate prenatal and postnatal echocardiography in fetuses with increased nuchal translucency (NT) with normal karyotype. METHODS: In this retrospective study, data on the screening of fetuses in pregnant women between 2014 and 2015 were evaluated. The fetuses at the gestational age were 14–11 weeks, and NT ≥ 95 percentile (or 3 mm). For all fetuses with increased NT, follow-up anomaly scan was performed at 18–22 weeks of pregnancy, while fetal echocardiography was performed at weeks 16–19 of pregnancy. The results were analyzed by Statistical Package for the Social Sciences (version 22) and the level of significance was less than 0.05. RESULTS: A total of 26.27% of the fetuses were diagnosed with prenatal heart defects and confirmed after birth. The strongest relationship was observed between increased NT and the diagnosis of prenatal heart defects at 2.5–5.3 mm. The increased NT was higher in younger mothers. Moreover, increased NT was higher in mothers with less body mass index. CONCLUSION: By measuring NT in the 11–13 weeks of pregnancy and considering the risk factors, it is possible to evaluate the probability of cardiac abnormalities in the fetus and perform the necessary diagnostic evaluations for high-risk cases. Wolters Kluwer - Medknow 2019-08-28 /pmc/articles/PMC6753816/ /pubmed/31548952 http://dx.doi.org/10.4103/jfmpc.jfmpc_395_19 Text en Copyright: © 2019 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Emami-Moghaddam, Abdolrahman
Barati, Mojgan
Amirpour, Razie
Shojaei, Kobra
Prenatal and postnatal echocardiography in NT fetuses with normal karyotype
title Prenatal and postnatal echocardiography in NT fetuses with normal karyotype
title_full Prenatal and postnatal echocardiography in NT fetuses with normal karyotype
title_fullStr Prenatal and postnatal echocardiography in NT fetuses with normal karyotype
title_full_unstemmed Prenatal and postnatal echocardiography in NT fetuses with normal karyotype
title_short Prenatal and postnatal echocardiography in NT fetuses with normal karyotype
title_sort prenatal and postnatal echocardiography in nt fetuses with normal karyotype
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753816/
https://www.ncbi.nlm.nih.gov/pubmed/31548952
http://dx.doi.org/10.4103/jfmpc.jfmpc_395_19
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