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Micro-PET Imaging Demonstrates 3-O-β-D-Glucopyranosyl Platycodigenin as an Effective Metabolite Affects Permeability of Cell Membrane and Improves Dosimetry of [(18)F]-Phillygenin in Lung Tissue

Platycodon grandiflorum, as a traditional medicinal plant, is commonly used in the treatment of pulmonary disease. Platycodon saponins are proposed as active ingredients. However, the role of secondary saponin metabolites (SSM) in the traditional use of Platycodon has not yet been fully clarified. I...

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Detalles Bibliográficos
Autores principales:	Shen, Fukui, Wu, Wenbo, Zhang, Man, Ma, Xiaoyao, Cui, Qingxin, Tang, Zhongyao, Huang, Hao, Tong, Tiantian, Yau, Leefong, Jiang, Zhihong, Hou, Yuanyuan, Bai, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753856/ https://www.ncbi.nlm.nih.gov/pubmed/31572193 http://dx.doi.org/10.3389/fphar.2019.01020

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