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Non-Functional Trace Amine-Associated Receptor 1 Variants in Patients With Mental Disorders
Background: The G protein–coupled receptor (GPCR) trace amine-associated receptor 1 (TAAR1) is expressed across brain areas involved in emotions, reward and cognition, and modulates monoaminergic and glutamatergic neurotransmissions. TAAR1 is stimulated with nanomolar affinity by 3-iodothyronamine (...
Autores principales: | Rutigliano, Grazia, Bräunig, Julia, Del Grande, Claudia, Carnicelli, Vittoria, Masci, Isabella, Merlino, Sergio, Kleinau, Gunnar, Tessieri, Luca, Pardossi, Simone, Paisdzior, Sarah, Dell’Osso, Liliana, Biebermann, Heike, Zucchi, Riccardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6753877/ https://www.ncbi.nlm.nih.gov/pubmed/31572197 http://dx.doi.org/10.3389/fphar.2019.01027 |
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