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Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome

Many patients with colorectal cancer are overweight. Even then, nutritional status is a frequently underestimated risk factor for perioperative complications. Enhanced Recovery after Surgery is the goal for perioperative management, and preoperative nutritional risk screening should be a standard. I...

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Detalles Bibliográficos
Autor principal: Weimann, Arved
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754043/
https://www.ncbi.nlm.nih.gov/pubmed/31579766
http://dx.doi.org/10.1515/iss-2017-0039
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author Weimann, Arved
author_facet Weimann, Arved
author_sort Weimann, Arved
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description Many patients with colorectal cancer are overweight. Even then, nutritional status is a frequently underestimated risk factor for perioperative complications. Enhanced Recovery after Surgery is the goal for perioperative management, and preoperative nutritional risk screening should be a standard. In case of nutritional risk, perioperative nutrition therapy should be started without delay and should follow recent guideline recommendations. The preservation of the microbiome has an emerging role in preventing postoperative anastomotic leakage and septic complications. The time window for recovery after neoadjuvant treatment for rectal cancer may be used for conditioning appropriate-risk patients in a “prehabilitation” program. In order to assess metabolic recovery and the prognosis for long-term survival, C-reactive protein/albumin ratio may be a promising parameter, which has to be validated in the future. This narrative review summarizes recent strategies and guideline recommendations.
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spelling pubmed-67540432019-10-02 Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome Weimann, Arved Innov Surg Sci Reviews Many patients with colorectal cancer are overweight. Even then, nutritional status is a frequently underestimated risk factor for perioperative complications. Enhanced Recovery after Surgery is the goal for perioperative management, and preoperative nutritional risk screening should be a standard. In case of nutritional risk, perioperative nutrition therapy should be started without delay and should follow recent guideline recommendations. The preservation of the microbiome has an emerging role in preventing postoperative anastomotic leakage and septic complications. The time window for recovery after neoadjuvant treatment for rectal cancer may be used for conditioning appropriate-risk patients in a “prehabilitation” program. In order to assess metabolic recovery and the prognosis for long-term survival, C-reactive protein/albumin ratio may be a promising parameter, which has to be validated in the future. This narrative review summarizes recent strategies and guideline recommendations. De Gruyter 2017-12-09 /pmc/articles/PMC6754043/ /pubmed/31579766 http://dx.doi.org/10.1515/iss-2017-0039 Text en ©2018 Weimann A., published by De Gruyter, Berlin/Boston http://creativecommons.org/licenses/by-nc-nd/4.0 This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.
spellingShingle Reviews
Weimann, Arved
Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome
title Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome
title_full Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome
title_fullStr Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome
title_full_unstemmed Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome
title_short Influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome
title_sort influence of nutritional status on postoperative outcome in patients with colorectal cancer – the emerging role of the microbiome
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754043/
https://www.ncbi.nlm.nih.gov/pubmed/31579766
http://dx.doi.org/10.1515/iss-2017-0039
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