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Human Autoantibodies Against N-Methyl-D-Aspartate Receptor Modestly Alter Dopamine D1 Receptor Surface Dynamics

Circulating autoantibodies directed against extracellular domains of the glutamatergic N-methyl-D-aspartate receptors (NMDAR-Ab) elicit psychotic symptoms in humans and behavioral deficits in animal models. Recent advances suggest that NMDAR-Ab exert their pathogenic action by altering the trafficki...

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Detalles Bibliográficos
Autores principales: Gréa, Hélène, Bouchet, Delphine, Rogemond, Véronique, Hamdani, Nora, Le Guen, Emmanuel, Tamouza, Ryad, Darrau, Estelle, Passerieux, Christine, Honnorat, Jérôme, Leboyer, Marion, Groc, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754069/
https://www.ncbi.nlm.nih.gov/pubmed/31572244
http://dx.doi.org/10.3389/fpsyt.2019.00670