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Human Autoantibodies Against N-Methyl-D-Aspartate Receptor Modestly Alter Dopamine D1 Receptor Surface Dynamics
Circulating autoantibodies directed against extracellular domains of the glutamatergic N-methyl-D-aspartate receptors (NMDAR-Ab) elicit psychotic symptoms in humans and behavioral deficits in animal models. Recent advances suggest that NMDAR-Ab exert their pathogenic action by altering the trafficki...
Autores principales: | Gréa, Hélène, Bouchet, Delphine, Rogemond, Véronique, Hamdani, Nora, Le Guen, Emmanuel, Tamouza, Ryad, Darrau, Estelle, Passerieux, Christine, Honnorat, Jérôme, Leboyer, Marion, Groc, Laurent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754069/ https://www.ncbi.nlm.nih.gov/pubmed/31572244 http://dx.doi.org/10.3389/fpsyt.2019.00670 |
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