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Neurobiology of rapid acting antidepressants: convergent effects on GluA1-synaptic function

Efforts to develop efficacious antidepressant agents with novel mechanisms have largely unsuccessful since the 1950’s until the discovery of ketamine, an NMDA receptor antagonist that produces rapid and sustained antidepressant actions even in treatment resistant patients. This finding has ushered a...

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Detalles Bibliográficos
Autores principales:	Duman, Ronald S., Shinohara, Ryota, Fogaça, Manoela V., Hare, Brendan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754322/ https://www.ncbi.nlm.nih.gov/pubmed/30894661 http://dx.doi.org/10.1038/s41380-019-0400-x

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