Cargando…

Compound danshen dripping pills normalize a reprogrammed metabolism of myocardial ischemia rats to interpret its time-dependent efficacy in clinic trials: a metabolomic study

INTRODUCTION: Clinical trials of Compound danshen dripping pills (CDDP) indicated distinct improvement in patients with chronic stable angina. Daily fluctuation of therapeutic effect agreed with a peak-valley PK profile during a 4-week CDDP regimen, but stabilized after 8-week treatment. OBJECTIVES:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aa, Nan, Guo, Jia-Hua, Cao, Bei, Sun, Run-Bin, Ma, Xiao-Hui, Chu, Yang, Zhou, Shui-Ping, Aa, Ji-Ye, Yang, Zhi-Jian, Sun, He, Wang, Guang-Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754357/ https://www.ncbi.nlm.nih.gov/pubmed/31541307 http://dx.doi.org/10.1007/s11306-019-1577-3

Ejemplares similares

Compound danshen dripping pills modulate the perturbed energy metabolism in a rat model of acute myocardial ischemia
por: Guo, Jiahua, et al.
Publicado: (2016)

Proangiogenesis effects of compound danshen dripping pills in zebrafish
por: Hu, Yang-Xi, et al.
Publicado: (2022)

Recommendations on the Clinical Use of Compound Danshen Dripping Pills
Publicado: (2017)

Metabonomic Strategy to the Evaluation of Chinese Medicine Compound Danshen Dripping Pills Interfering Myocardial Ischemia in Rats
por: Xin, Xue, et al.
Publicado: (2013)

Compound Danshen Dripping Pill Inhibits Retina Cell Apoptosis in Diabetic Rats
por: Zhang, Qian, et al.
Publicado: (2018)

Synergistic Effects of Clopidogrel and Fufang Danshen Dripping Pills by Modulation of the Metabolism Target and Pharmacokinetics
por: Ma, Shitang, et al.
Publicado: (2014)

Coadministration of Compound Danshen dripping pills and bezafibrate has a protective effect against diabetic retinopathy
por: Liu, Le, et al.
Publicado: (2022)

Compound Danshen dripping pills in treating with coronary heart disease: A protocol for systematic review and meta-analysis
por: Sun, Ling, et al.
Publicado: (2022)

The Efficacy and Safety of Compound Danshen Dripping Pill Combined with Percutaneous Coronary Intervention for Coronary Heart Disease
por: Li, Cailan, et al.
Publicado: (2020)

Compound danshen dripping pills vs. nitrates for stable angina pectoris: a systematic review and meta-analysis
por: Zhang, Mengying, et al.
Publicado: (2023)

Compound Danshen Dripping Pill inhibits high altitude-induced hypoxic damage by suppressing oxidative stress and inflammatory responses
por: Hu, Yunhui, et al.
Publicado: (2021)

Pre-treatment with compound Danshen dripping pills prevents lipid infusion-induced microvascular dysfunction in mice
por: Zhang, Yanda, et al.
Publicado: (2020)

The Relationship between Compound Danshen Dripping Pills with Isosorbide Mononitrate in the Treatment of Elderly Patients with Unstable Angina Pectoris
por: Liang, Yulin, et al.
Publicado: (2018)

Systematic review and Meta-analysis of 26 randomized controlled clinical trials of Compound Danshen Dripping Pill for non-proliferating diabetic retinopathy
por: Wang, Yu, et al.
Publicado: (2021)

Compound Danshen Dripping Pill for Treating Early Diabetic Retinopathy: A Randomized, Double-Dummy, Double-Blind Study
por: Luo, Dan, et al.
Publicado: (2015)

Compound Danshen Dripping Pill for Treating Nonproliferative Diabetic Retinopathy: A Meta-Analysis of 13 Randomized Controlled Trials
por: Huang, Wenjing, et al.
Publicado: (2017)

Compound Danshen Dripping Pill Pretreatment to Prevent Contrast-Induced Nephropathy in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
por: Yang, Rong, et al.
Publicado: (2014)

Compound Danshen Dripping Pill inhibits hypercholesterolemia/atherosclerosis-induced heart failure in ApoE and LDLR dual deficient mice via multiple mechanisms
por: Yang, Yanfang, et al.
Publicado: (2023)

Compound danshen dripping pills combined with trimetazidine in treating unstable angina pectoris: Protocol for a systematic review of randomized controlled trials
por: Yao, Dongfeng, et al.
Publicado: (2019)

Compound Danshen Dripping Pills Prevented Leptin Deficiency-Induced Hepatic ER Stress, Stimulated Autophagy, and Improved Insulin Resistance of ob/ob Mice
por: Shi, Yanan, et al.
Publicado: (2020)

Effectiveness and Safety of Fufang Danshen Dripping Pill (Cardiotonic Pill) on Blood Viscosity and Hemorheological Factors for Cardiovascular Event Prevention in Patients with Type 2 Diabetes Mellitus: Systematic Review and Meta-Analysis
por: Wi, Minji, et al.
Publicado: (2023)

Protective effect of compound Danshen (Salvia miltiorrhiza) dripping pills alone and in combination with carbamazepine on kainic acid-induced temporal lobe epilepsy and cognitive impairment in rats
por: Jia, Chen, et al.
Publicado: (2018)

Systematic Review of Compound Danshen Dropping Pill: A Chinese Patent Medicine for Acute Myocardial Infarction
por: Luo, Jing, et al.
Publicado: (2013)

Elucidating direct kinase targets of compound Danshen dropping pills employing archived data and prediction models
por: Wang, Tongxing, et al.
Publicado: (2021)

Musk Tongxin Dripping Pills for treating Ticagrelor in Patients After Percutaneous Coronary Intervention: Echocardiography Combined with Untargeted Metabolomics
por: Nan, Lyu, et al.
Publicado: (2021)

Neuroprotective Effects of Qingnao Dripping Pills Against Cerebral Ischemia via Inhibiting NLRP3 Inflammasome Signaling Pathway: In Vivo and In Vitro
por: Fu, Chen, et al.
Publicado: (2020)

Integrated network pharmacology and metabolomics to reveal the mechanism of QiShenYiQi Dripping Pills against cardiac structural and functional abnormalities
por: Zhang, Jun, et al.
Publicado: (2022)

QishenYiqi dripping pill protects against myocardial ischemia/reperfusion injury via suppressing excessive autophagy and NLRP3 inflammasome based on network pharmacology and experimental pharmacology
por: Li, Meng, et al.
Publicado: (2022)

Guanxin Danshen Formulation Protects against Myocardial Ischemia Reperfusion Injury-Induced Left Ventricular Remodeling by Upregulating Estrogen Receptor β
por: Deng, Xuehong, et al.
Publicado: (2017)

Corrigendum: Integrated network pharmacology and metabolomics to reveal the mechanism of QiShenYiQi Dripping Pills against cardiac structural and functional abnormalities
por: Zhang, Jun, et al.
Publicado: (2022)

Efficacy of INtensive Treatment vs. Standard Treatment of COmpound DanshEn Dripping Pills in Refractory Angina Patients With Incomplete Revascularization (INCODER Study): Study Protocol for a Multicenter, Double-Blind, Randomized Controlled, Superiority Trial
por: Wu, Zexuan, et al.
Publicado: (2022)

Investigating the molecular mechanism of Compound Danshen Dropping Pills for the treatment of epilepsy by utilizing network pharmacology and molecular docking technology
por: Huang, Dan, et al.
Publicado: (2022)

Qi-Shen-Yi-Qi Dripping Pills for the Secondary Prevention of Myocardial Infarction: A Randomised Clinical Trial
por: Shang, Hongcai, et al.
Publicado: (2013)

TMT-based quantitative proteomics analysis of the effects of Jiawei Danshen decoction myocardial ischemia-reperfusion injury
por: Zhu, Xiang-Mei, et al.
Publicado: (2022)

Real-time quality control of dripping pill’s weight based on laser detection technology
por: Wang, Xiaoping, et al.
Publicado: (2023)

An Integrative Pharmacology-Based Pattern to Uncover the Pharmacological Mechanism of Ginsenoside H Dripping Pills in the Treatment of Depression
por: Zhao, Libin, et al.
Publicado: (2021)

Identification of Pharmacokinetic Markers for Guanxin Danshen Drop Pills in Rats by Combination of Pharmacokinetics, Systems Pharmacology, and Pharmacodynamic Assays
por: Yao, Hong, et al.
Publicado: (2018)

Evaluation and clinical implications of interactions between compound Danshen dropping pill and warfarin associated with the epoxide hydrolase gene
por: Chen, Xixi, et al.
Publicado: (2023)

Neuroprotective effects of tanshinone I from Danshen extract in a mouse model of hypoxia-ischemia
por: Lee, Jae-Chul, et al.
Publicado: (2013)

Qishen Yiqi dripping pills for chronic ischaemic heart failure: results of the CACT‐IHF randomized clinical trial
por: Mao, Jingyuan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ckapm1djhtidbq36v1278469sl