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Class Id ribonucleotide reductase utilizes a Mn(2)(IV,III) cofactor and undergoes large conformational changes on metal loading
Outside of the photosynthetic machinery, high-valent manganese cofactors are rare in biology. It was proposed that a recently discovered subclass of ribonucleotide reductase (RNR), class Id, is dependent on a Mn(2)(IV,III) cofactor for catalysis. Class I RNRs consist of a substrate-binding component...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754362/ https://www.ncbi.nlm.nih.gov/pubmed/31414238 http://dx.doi.org/10.1007/s00775-019-01697-8 |