Class Id ribonucleotide reductase utilizes a Mn(2)(IV,III) cofactor and undergoes large conformational changes on metal loading

Outside of the photosynthetic machinery, high-valent manganese cofactors are rare in biology. It was proposed that a recently discovered subclass of ribonucleotide reductase (RNR), class Id, is dependent on a Mn(2)(IV,III) cofactor for catalysis. Class I RNRs consist of a substrate-binding component...

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Detalles Bibliográficos
Autores principales: Rozman Grinberg, Inna, Berglund, Sigrid, Hasan, Mahmudul, Lundin, Daniel, Ho, Felix M., Magnuson, Ann, Logan, Derek T., Sjöberg, Britt-Marie, Berggren, Gustav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754362/
https://www.ncbi.nlm.nih.gov/pubmed/31414238
http://dx.doi.org/10.1007/s00775-019-01697-8

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