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Enhancing innate antiviral immune responses in rainbow trout by double stranded RNA delivered with cationic phytoglycogen nanoparticles
Innate immunity is induced when pathogen-associated molecular patterns (PAMPs) bind host pattern recognition receptors (PRRs). Polyinosinic:polycytidylic acid [poly(I:C)] is a synthetic analogue of viral dsRNA that acts as a PAMP, inducing type I interferons (IFNs) in vertebrates. In the present stu...
Autores principales: | Alkie, Tamiru N., de Jong, Jondavid, Jenik, Kristof, Klinger, Karl M., DeWitte-Orr, Stephanie J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754369/ https://www.ncbi.nlm.nih.gov/pubmed/31541160 http://dx.doi.org/10.1038/s41598-019-49931-2 |
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