Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion

The accumulation of advanced glycation end products (AGEs) have been implicated in the development and progression of diabetic kidney disease (DKD). There has been interest in investigating the potential of AGE clearance receptors, such as oligosaccharyltransferase-48 kDa subunit (OST48) to prevent...

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Detalles Bibliográficos
Autores principales: Zhuang, Aowen, Yap, Felicia Y. T., McCarthy, Domenica, Leung, Chris, Sourris, Karly C., Penfold, Sally A., Thallas-Bonke, Vicki, Coughlan, Melinda T., Schulz, Benjamin L., Forbes, Josephine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754370/
https://www.ncbi.nlm.nih.gov/pubmed/31541173
http://dx.doi.org/10.1038/s41598-019-50221-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754370/
https://www.ncbi.nlm.nih.gov/pubmed/31541173
http://dx.doi.org/10.1038/s41598-019-50221-0

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