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Mycobacterium tuberculosis sensor kinase DosS modulates the autophagosome in a DosR-independent manner

Dormancy is a key characteristic of the intracellular life-cycle of Mtb. The importance of sensor kinase DosS in mycobacteria are attributed in part to our current findings that DosS is required for both persistence and full virulence of Mtb. Here we show that DosS is also required for optimal repli...

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Detalles Bibliográficos
Autores principales: Gautam, Uma S., Mehra, Smriti, Kumari, Priyanka, Alvarez, Xavier, Niu, Tianhua, Tyagi, Jaya S., Kaushal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754383/
https://www.ncbi.nlm.nih.gov/pubmed/31552302
http://dx.doi.org/10.1038/s42003-019-0594-0