Cargando…

Ran pathway-independent regulation of mitotic Golgi disassembly by Importin-α

To facilitate proper mitotic cell partitioning, the Golgi disassembles by suppressing vesicle fusion. However, the underlying mechanism has not been characterized previously. Here, we report a Ran pathway-independent attenuation mechanism that allows Importin-α (a nuclear transport factor) to suppre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chang, Chih-Chia, Chen, Ching-Jou, Grauffel, Cédric, Pien, Yu-Chung, Lim, Carmay, Tsai, Su-Yi, Hsia, Kuo-Chiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754406/ https://www.ncbi.nlm.nih.gov/pubmed/31541088 http://dx.doi.org/10.1038/s41467-019-12207-4

Ejemplares similares

Regulation of mitotic spindle assembly factor NuMA by Importin-β
por: Chang, Chih-Chia, et al.
Publicado: (2017)

Sequential phosphorylation of GRASP65 during mitotic Golgi disassembly
por: Tang, Danming, et al.
Publicado: (2012)

How Native and Alien Metal Cations Bind ATP: Implications for Lithium as a Therapeutic Agent
por: Dudev, Todor, et al.
Publicado: (2017)

An Ordered Inheritance Strategy for the Golgi Apparatus: Visualization of Mitotic Disassembly Reveals a Role for the Mitotic Spindle
por: Shima, David T., et al.
Publicado: (1998)

RanBP2 stops importin-β from running away
por: Leslie, Mitch
Publicado: (2011)

Microtubule binding of the human augmin complex is directly controlled by importins and Ran-GTP
por: Ustinova, Kseniya, et al.
Publicado: (2023)

Trinuclear Calcium Site in the C2 Domain of PKCα/γ Is Prone to Lithium Attack
por: Grauffel, Cédric, et al.
Publicado: (2021)

Ran-dependent docking of importin-β to RanBP2/Nup358 filaments is essential for protein import and cell viability
por: Hamada, Masakazu, et al.
Publicado: (2011)

Mek and Cdc2 Kinase Are Sequentially Required for Golgi Disassembly in Mdck Cells by the Mitotic Xenopus Extracts
por: Kano, Fumi, et al.
Publicado: (2000)

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner
por: Lowe, Alan R, et al.
Publicado: (2015)

Molecular basis for disassembly of an importin:ribosomal protein complex by the escortin Tsr2
por: Schütz, Sabina, et al.
Publicado: (2018)

The importin-β binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro
por: Huber, Jochen, et al.
Publicado: (2002)

Importin-β and the small guanosine triphosphatase Ran mediate chromosome loading of the human chromokinesin Kid
por: Tahara, Kiyoshi, et al.
Publicado: (2008)

Dynamics of the STAT3 Transcription Factor: Nuclear Import Dependent on Ran and Importin-β1
por: Cimica, Velasco, et al.
Publicado: (2011)

Moonlighting of mitotic regulators in cilium disassembly
por: Doornbos, Cenna, et al.
Publicado: (2021)

RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly
por: Swaminathan, Sowmya, et al.
Publicado: (2004)

Ciliary entry of the kinesin-2 motor KIF17 is regulated by importin-β2 and Ran-GTP
por: Dishinger, John F., et al.
Publicado: (2010)

Structural analysis of disease-related TDP-43 D169G mutation: linking enhanced stability and caspase cleavage efficiency to protein accumulation
por: Chiang, Chien-Hao, et al.
Publicado: (2016)

RanGTP induces an effector gradient of XCTK2 and importin α/β for spindle microtubule cross-linking
por: Ems-McClung, Stephanie C., et al.
Publicado: (2019)

Golgi clusters and vesicles mediate mitotic inheritance independently of the endoplasmic reticulum
por: Jokitalo, Eija, et al.
Publicado: (2001)

Efficient Strategy to Design Protease Inhibitors: Application to Enterovirus 71 2A Protease
por: Chen, Ting, et al.
Publicado: (2022)

Allosteric coupling between transmembrane segment 4 and the selectivity filter of TALK1 potassium channels regulates their gating by extracellular pH
por: Tsai, Wen-Hao, et al.
Publicado: (2022)

RanBP1 controls the Ran pathway in mammalian cells through regulation of mitotic RCC1 dynamics
por: Yau, Ka Chun, et al.
Publicado: (2020)

RanGTP and CLASP1 cooperate to position the mitotic spindle
por: Bird, Stephen L., et al.
Publicado: (2013)

Mitotic lamin disassembly is triggered by lipid-mediated signaling
por: Mall, Moritz, et al.
Publicado: (2012)

SUMO-1 targets RanGAP1 to kinetochores and mitotic spindles
por: Joseph, Jomon, et al.
Publicado: (2002)

Mitotic spindle scaling during Xenopus development by kif2a and importin α
por: Wilbur, Jeremy D, et al.
Publicado: (2013)

Anaplasma phagocytophilum Ankyrin A Protein (AnkA) Enters the Nucleus Using an Importin-β-, RanGTP-Dependent Mechanism
por: Kim, Yuri, et al.
Publicado: (2022)

Mitotic spindle ties the Golgi ribbon
por: Short, Ben
Publicado: (2009)

SUMOylation mediates the disassembly of the Smad4 nuclear export complex via RanGAP1 in KELOIDS
por: Lin, Xiaohu, et al.
Publicado: (2023)

Mitotic replisome disassembly depends on TRAIP ubiquitin ligase activity
por: Priego Moreno, Sara, et al.
Publicado: (2019)

Sequential Depletion and Acquisition of Proteins during Golgi Stack Disassembly and Reformation
por: Schoberer, Jennifer, et al.
Publicado: (2010)

Golgi-associated BICD adaptors couple ER membrane penetration and disassembly of a viral cargo
por: Spriggs, Chelsey C., et al.
Publicado: (2020)

Thioredoxin-related transmembrane protein 2 (TMX2) regulates the Ran protein gradient and importin-β-dependent nuclear cargo transport
por: Oguro, Ami, et al.
Publicado: (2019)

Molecular basis of RanGTP-activated nucleosome assembly with Histones H2A-H2B bound to Importin-9
por: Shaffer, Joy M., et al.
Publicado: (2023)

Mechanisms and Regulation of the Mitotic Inheritance of the Golgi Complex
por: Valente, Carmen, et al.
Publicado: (2015)

The importin beta superfamily member RanBP17 exhibits a role in cell proliferation and is associated with improved survival of patients with HPV+ HNSCC
por: Mandic, Robert, et al.
Publicado: (2022)

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
por: Sargsyan, Karen, et al.
Publicado: (2020)

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes
por: Ritterhoff, Tobias, et al.
Publicado: (2016)

Release of condensin from mitotic chromosomes requires the Ran-GTP gradient in the reorganized nucleus
por: Aoki, Keita, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_mt6qoo1mjneustqerh89ehu38u