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Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma
Medulloblastoma is a malignant pediatric tumor that arises from neural progenitors in the cerebellum. Despite a five-year survival rate of ~70%, nearly all patients incur adverse side effects from current treatment strategies that drastically impact quality of life. Roughly one-third of medulloblast...
Autores principales: | Robinson, M. Hope, Maximov, Victor, Lallani, Shoeb, Farooq, Hamza, Taylor, Michael D., Read, Renee D., Kenney, Anna Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754407/ https://www.ncbi.nlm.nih.gov/pubmed/31541170 http://dx.doi.org/10.1038/s41598-019-50088-1 |
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