Plasmodium vivax chloroquine resistance links to pvcrt transcription in a genetic cross

Mainstay treatment for Plasmodium vivax malaria has long relied on chloroquine (CQ) against blood-stage parasites plus primaquine against dormant liver-stage forms (hypnozoites), however drug resistance confronts this regimen and threatens malaria control programs. Understanding the basis of P. viva...

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Detalles Bibliográficos
Autores principales: Sá, Juliana M., Kaslow, Sarah R., Moraes Barros, Roberto R., Brazeau, Nicholas F., Parobek, Christian M., Tao, Dingyin, Salzman, Rebecca E., Gibson, Tyler J., Velmurugan, Soundarapandian, Krause, Michael A., Melendez-Muniz, Viviana, Kite, Whitney A., Han, Paul K., Eastman, Richard T., Kim, Adam, Kessler, Evan G., Abebe, Yonas, James, Eric R., Chakravarty, Sumana, Orr-Gonzalez, Sachy, Lambert, Lynn E., Engels, Theresa, Thomas, Marvin L., Fasinu, Pius S., Serre, David, Gwadz, Robert W., Walker, Larry, DeConti, Derrick K., Mu, Jianbing, Bailey, Jeffrey A., Sim, B. Kim Lee, Hoffman, Stephen L., Fay, Michael P., Dinglasan, Rhoel R., Juliano, Jonathan J., Wellems, Thomas E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754410/
https://www.ncbi.nlm.nih.gov/pubmed/31541097
http://dx.doi.org/10.1038/s41467-019-12256-9

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