Refinements of LC-MS/MS Spectral Counting Statistics Improve Quantification of Low Abundance Proteins

Mass spectrometry-based spectral count has been a common choice of label-free proteome quantification due to the simplicity for the sample preparation and data generation. The discriminatory nature of spectral count in the MS data-dependent acquisition, however, inherently introduces the spectral co...

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Detalles Bibliográficos
Autores principales: Lee, Ha Yun, Kim, Eunhee G., Jung, Hye Ryeon, Jung, Jin Woo, Kim, Han Byeol, Cho, Jin Won, Kim, Kristine M., Yi, Eugene C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754416/
https://www.ncbi.nlm.nih.gov/pubmed/31541118
http://dx.doi.org/10.1038/s41598-019-49665-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754416/
https://www.ncbi.nlm.nih.gov/pubmed/31541118
http://dx.doi.org/10.1038/s41598-019-49665-1

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