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Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 (ST8SIA2) synthesizes polysialic acid (PSA), which is essential for brain development. Although previous studies reported that St8sia2-deficient mice that have a mixed 129 and C57BL/6 (B6) genetic background showed mild and variable phenot...

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Detalles Bibliográficos
Autores principales:	Ikegami, Keisuke, Saigoh, Kazumasa, Fujioka, Atsuko, Nagano, Mamoru, Kitajima, Ken, Sato, Chihiro, Masubuchi, Satoru, Kusunoki, Susumu, Shigeyoshi, Yasufumi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754417/ https://www.ncbi.nlm.nih.gov/pubmed/31541165 http://dx.doi.org/10.1038/s41598-019-50006-5

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