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Chromosomal instability of circulating tumor DNA reflect therapeutic responses in advanced gastric cancer

Gastric cancer is characterized by chromosomal instability. In this study, we investigated chromosomal instability quantified by copy number instability (CNI) score of circulating tumor DNA (ctDNA) during the drug treatment in advanced gastric cancer (AGC). A total of 55 pretherapeutic plasmas from...

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Detalles Bibliográficos
Autores principales: Chen, Zuhua, Zhang, Cheng, Zhang, Mengqi, Li, Beifang, Niu, Yunyun, Chen, Limeng, Yang, Jing, Lu, Sijia, Gao, Jing, Shen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754425/
https://www.ncbi.nlm.nih.gov/pubmed/31541076
http://dx.doi.org/10.1038/s41419-019-1907-4

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