IgG4 antibodies from patients with asymptomatic bancroftian filariasis inhibit the binding of IgG1 and IgG2 to C1q in a Fc-Fc-dependent mechanism

A striking feature of lymphatic filariasis (LF) is the clinical heterogeneity among exposed individuals. While endemic normals (EN) remain free of infection despite constant exposure to the infective larvae, a small group of patients, generally microfilaria free (Mf-) develops severe pathology (CP)...

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Detalles Bibliográficos
Autores principales: Prodjinotho, Ulrich F., Hoerauf, Achim, Adjobimey, Tomabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Immunology and Host-Parasite Interactions - Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754495/
https://www.ncbi.nlm.nih.gov/pubmed/31485865
http://dx.doi.org/10.1007/s00436-019-06451-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754495/
https://www.ncbi.nlm.nih.gov/pubmed/31485865
http://dx.doi.org/10.1007/s00436-019-06451-2

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