Carbocisteine inhibits the expression of Muc5b in COPD mouse model

BACKGROUND: Cigarette smoke (CS) results in chronic mucus hypersecretion and airway inflammation, contributing to COPD pathogenesis. Mucin 5B (MUC5B) and mucin 5 AC (MUC5AC) are major mucins implicated in COPD pathogenesis. Carbocisteine can reduce mucus viscosity and elasticity. Although carbociste...

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Detalles Bibliográficos
Autores principales: Song, Yan, Wang, Wei, Xie, Yanqing, Xiang, Bin, Huang, Xuan, Guan, Weijie, Zheng, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754527/
https://www.ncbi.nlm.nih.gov/pubmed/31571828
http://dx.doi.org/10.2147/DDDT.S198874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754527/
https://www.ncbi.nlm.nih.gov/pubmed/31571828
http://dx.doi.org/10.2147/DDDT.S198874

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