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Molecular basis for retinol binding by serum amyloid A during infection

Serum amyloid A (SAA) proteins are strongly induced in the liver by systemic infection and in the intestine by bacterial colonization. In infected mice, SAA proteins circulate in association with the vitamin A derivative retinol, suggesting that SAAs transport retinol during infection. Here we illum...

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Detalles Bibliográficos
Autores principales: Hu, Zehan, Bang, Ye-Ji, Ruhn, Kelly A., Hooper, Lora V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754605/
https://www.ncbi.nlm.nih.gov/pubmed/31484771
http://dx.doi.org/10.1073/pnas.1910713116