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Withaferin-A Inhibits Growth of Drug-Resistant Breast Carcinoma by Inducing Apoptosis and Autophagy, Endogenous Reactive Oxygen Species (ROS) Production, and Inhibition of Cell Migration and Nuclear Factor kappa B (Nf-κB)/Mammalian Target of Rapamycin (m-TOR) Signalling Pathway

BACKGROUND: The main purpose of this study was to assess in vitro and in vivo the anticancer effect of withaferin-A in human breast carcinoma cells (MDA-MB-231), and to assess its effects on autophagy, cell apoptosis, ROS production, cell migration and invasion, and Nf-κB/m-TOR signalling pathway. M...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaokang, Li, Yu, Ma, Qiang, Wang, Yanwei, Song, Ai Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2019
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754708/ https://www.ncbi.nlm.nih.gov/pubmed/31512681 http://dx.doi.org/10.12659/MSM.916931

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