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Primary angiosarcoma of the breast: a case report
Primary angiosarcoma of the breast is an extremely rare tumour with a difficult diagnosis and poor prognosis. We report a case of primary breast angiosarcoma diagnosed in the pathology department of the University Hospital of Oujda. An analysis of the epidemiological, diagnostic and therapeutic aspe...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The African Field Epidemiology Network
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754832/ https://www.ncbi.nlm.nih.gov/pubmed/31558933 http://dx.doi.org/10.11604/pamj.2019.33.134.17414 |
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author | Mouhoub, Mohamed Miry, Achraf Haloui, Anass Karich, Nassira Kamaoui, Imane Benkirane, Saad Bennani, Amal |
author_facet | Mouhoub, Mohamed Miry, Achraf Haloui, Anass Karich, Nassira Kamaoui, Imane Benkirane, Saad Bennani, Amal |
author_sort | Mouhoub, Mohamed |
collection | PubMed |
description | Primary angiosarcoma of the breast is an extremely rare tumour with a difficult diagnosis and poor prognosis. We report a case of primary breast angiosarcoma diagnosed in the pathology department of the University Hospital of Oujda. An analysis of the epidemiological, diagnostic and therapeutic aspects of this type of tumour is made in this manuscript. Mastectomy is the standard treatment; the place of radiotherapy and chemotherapy is not well established. We report a case of a 18- year-old woman having an infectious symptomatology of the right breast for which she received an anti-infectious therapy inducing regression of inflammatory symptoms presented with a quick growing mass. Initial core needle biopsy showed a malignant vascular proliferation. The patient underwent a mastectomy. The tumor histology showed papillary formations and vascular structures lined by atypical cells with hyperchromatic nucleus and eosinophilic cytoplasm. The tumor cells expressed CD34 and CD31 but were negative for cytokeratin. The diagnosis of angiosarcoma grade I was made. The patient is now receiving chemotherapy. She is still alive. |
format | Online Article Text |
id | pubmed-6754832 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The African Field Epidemiology Network |
record_format | MEDLINE/PubMed |
spelling | pubmed-67548322019-09-26 Primary angiosarcoma of the breast: a case report Mouhoub, Mohamed Miry, Achraf Haloui, Anass Karich, Nassira Kamaoui, Imane Benkirane, Saad Bennani, Amal Pan Afr Med J Case Report Primary angiosarcoma of the breast is an extremely rare tumour with a difficult diagnosis and poor prognosis. We report a case of primary breast angiosarcoma diagnosed in the pathology department of the University Hospital of Oujda. An analysis of the epidemiological, diagnostic and therapeutic aspects of this type of tumour is made in this manuscript. Mastectomy is the standard treatment; the place of radiotherapy and chemotherapy is not well established. We report a case of a 18- year-old woman having an infectious symptomatology of the right breast for which she received an anti-infectious therapy inducing regression of inflammatory symptoms presented with a quick growing mass. Initial core needle biopsy showed a malignant vascular proliferation. The patient underwent a mastectomy. The tumor histology showed papillary formations and vascular structures lined by atypical cells with hyperchromatic nucleus and eosinophilic cytoplasm. The tumor cells expressed CD34 and CD31 but were negative for cytokeratin. The diagnosis of angiosarcoma grade I was made. The patient is now receiving chemotherapy. She is still alive. The African Field Epidemiology Network 2019-06-24 /pmc/articles/PMC6754832/ /pubmed/31558933 http://dx.doi.org/10.11604/pamj.2019.33.134.17414 Text en © Mohamed Mouhoub et al. http://creativecommons.org/licenses/by/2.0/ The Pan African Medical Journal - ISSN 1937-8688. This is an Open Access article distributed under the terms of the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Mouhoub, Mohamed Miry, Achraf Haloui, Anass Karich, Nassira Kamaoui, Imane Benkirane, Saad Bennani, Amal Primary angiosarcoma of the breast: a case report |
title | Primary angiosarcoma of the breast: a case report |
title_full | Primary angiosarcoma of the breast: a case report |
title_fullStr | Primary angiosarcoma of the breast: a case report |
title_full_unstemmed | Primary angiosarcoma of the breast: a case report |
title_short | Primary angiosarcoma of the breast: a case report |
title_sort | primary angiosarcoma of the breast: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754832/ https://www.ncbi.nlm.nih.gov/pubmed/31558933 http://dx.doi.org/10.11604/pamj.2019.33.134.17414 |
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