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Neuroprotective effects of an Nrf2 agonist on high glucose-induced damage in HT22 cells

BACKGROUND: Oxidative stress is the hallmark of diabetic encephalopathy, which may be caused by hyperglycaemic toxicity. We aimed to discover pharmacologic targets to restore redox homeostasis. We identified the transcription factor Nrf2 as such a target. METHODS: HT22 cells were cultured in 25 or 5...

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Detalles Bibliográficos
Autores principales:	Zhao, Jiangpei, Liu, Lerong, Li, Xia, Zhang, Lingxiao, Lv, Jing, Guo, Xueli, Chen, Hui, Zhao, Tongfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754858/ https://www.ncbi.nlm.nih.gov/pubmed/31542051 http://dx.doi.org/10.1186/s40659-019-0258-z

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