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Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study

OBJECTIVE: To examine the distribution of stage at diagnosis for 12 cancers in Kuwait, to estimate stage-specific net survival at 1 and 5 years after diagnosis, and to assess differences in stage-specific survival between Kuwait and the United States. MATERIAL AND METHODS: Data were obtained from th...

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Autores principales: Alawadhi, E., Al-Awadi, A., Elbasmi, A., Coleman, M. P., Allemani, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754911/
https://www.ncbi.nlm.nih.gov/pubmed/31662756
http://dx.doi.org/10.1155/2019/8463195
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author Alawadhi, E.
Al-Awadi, A.
Elbasmi, A.
Coleman, M. P.
Allemani, C.
author_facet Alawadhi, E.
Al-Awadi, A.
Elbasmi, A.
Coleman, M. P.
Allemani, C.
author_sort Alawadhi, E.
collection PubMed
description OBJECTIVE: To examine the distribution of stage at diagnosis for 12 cancers in Kuwait, to estimate stage-specific net survival at 1 and 5 years after diagnosis, and to assess differences in stage-specific survival between Kuwait and the United States. MATERIAL AND METHODS: Data were obtained from the Kuwait Cancer Registry, for Kuwaiti patients diagnosed during 2000–2013, with follow-up to 31 December 2015. The distribution of Surveillance Epidemiology and End Results (SEER) Summary Stage for 12 malignancies was examined. We estimated net survival by stage up to 5 years after diagnosis, controlling for background mortality with life tables of all-cause mortality in the general population by single year of age, sex, and calendar period. Survival estimates were age-standardised using the International Cancer Survival Standard (ICSS) weights. RESULTS: Only 14.2% of patients were diagnosed at a localised stage and 38.9% at the regional stage. The proportion of patients with known stage was 88.9% during 2000–2004 but fell to 59.4% during 2010–2013. During 2005–2009, 1- and 5-year survival for colon, rectal, breast, cervical, and prostate cancer was about 90% or higher for patients diagnosed at the localised stage. During 2004–2009, the proportion of patients diagnosed at a localised stage was lower in Kuwait than in the US for colon, breast, and lung cancer. Age-standardised 5-year net survival for all stages combined was lower in Kuwait than the US for colon, lung, and breast cancer, but stage-specific survival was similar. CONCLUSION: Since stage-specific survival is similar in Kuwait and the US, late stage at diagnosis is likely to be a major contributing factor to the overall lower survival in Kuwait than in the US. Increasing public awareness of cancer risk factors and symptoms and investment in early detection will be vital to reduce the proportion of patients diagnosed at a late stage and to improve survival.
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spelling pubmed-67549112019-10-29 Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study Alawadhi, E. Al-Awadi, A. Elbasmi, A. Coleman, M. P. Allemani, C. J Oncol Research Article OBJECTIVE: To examine the distribution of stage at diagnosis for 12 cancers in Kuwait, to estimate stage-specific net survival at 1 and 5 years after diagnosis, and to assess differences in stage-specific survival between Kuwait and the United States. MATERIAL AND METHODS: Data were obtained from the Kuwait Cancer Registry, for Kuwaiti patients diagnosed during 2000–2013, with follow-up to 31 December 2015. The distribution of Surveillance Epidemiology and End Results (SEER) Summary Stage for 12 malignancies was examined. We estimated net survival by stage up to 5 years after diagnosis, controlling for background mortality with life tables of all-cause mortality in the general population by single year of age, sex, and calendar period. Survival estimates were age-standardised using the International Cancer Survival Standard (ICSS) weights. RESULTS: Only 14.2% of patients were diagnosed at a localised stage and 38.9% at the regional stage. The proportion of patients with known stage was 88.9% during 2000–2004 but fell to 59.4% during 2010–2013. During 2005–2009, 1- and 5-year survival for colon, rectal, breast, cervical, and prostate cancer was about 90% or higher for patients diagnosed at the localised stage. During 2004–2009, the proportion of patients diagnosed at a localised stage was lower in Kuwait than in the US for colon, breast, and lung cancer. Age-standardised 5-year net survival for all stages combined was lower in Kuwait than the US for colon, lung, and breast cancer, but stage-specific survival was similar. CONCLUSION: Since stage-specific survival is similar in Kuwait and the US, late stage at diagnosis is likely to be a major contributing factor to the overall lower survival in Kuwait than in the US. Increasing public awareness of cancer risk factors and symptoms and investment in early detection will be vital to reduce the proportion of patients diagnosed at a late stage and to improve survival. Hindawi 2019-09-09 /pmc/articles/PMC6754911/ /pubmed/31662756 http://dx.doi.org/10.1155/2019/8463195 Text en Copyright © 2019 E. Alawadhi et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Alawadhi, E.
Al-Awadi, A.
Elbasmi, A.
Coleman, M. P.
Allemani, C.
Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study
title Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study
title_full Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study
title_fullStr Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study
title_full_unstemmed Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study
title_short Cancer Survival by Stage at Diagnosis in Kuwait: A Population-Based Study
title_sort cancer survival by stage at diagnosis in kuwait: a population-based study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754911/
https://www.ncbi.nlm.nih.gov/pubmed/31662756
http://dx.doi.org/10.1155/2019/8463195
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