Cargando…

Inhibition of Synovial Macrophage Pyroptosis Alleviates Synovitis and Fibrosis in Knee Osteoarthritis

Increasing evidence has shown that macrophage pyroptosis in different tissues participates in chronic aseptic inflammation and is related to tissue fibrosis. Our last studies also revealed the vital role of synovial fibroblast pyroptosis in the onset and development of knee osteoarthritis (KOA). In...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Li, Xing, Runlin, Huang, Zhengquan, Zhang, Nongshan, Li, Xiaochen, Wang, Peimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754937/ https://www.ncbi.nlm.nih.gov/pubmed/31582897 http://dx.doi.org/10.1155/2019/2165918

Ejemplares similares

Agnuside Alleviates Synovitis and Fibrosis in Knee Osteoarthritis through the Inhibition of HIF-1α and NLRP3 Inflammasome
por: Zhang, Li, et al.
Publicado: (2021)

Increased HIF-1α in Knee Osteoarthritis Aggravate Synovial Fibrosis via Fibroblast-Like Synoviocyte Pyroptosis
por: Zhang, Li, et al.
Publicado: (2019)

Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis
por: Zhang, Haosheng, et al.
Publicado: (2021)

Synovial Fibrosis Involvement in Osteoarthritis
por: Zhang, Li, et al.
Publicado: (2021)

Sanse Powder Essential Oil Nanoemulsion Negatively Regulates TRPA1 by AMPK/mTOR Signaling in Synovitis: Knee Osteoarthritis Rat Model and Fibroblast-Like Synoviocyte Isolates
por: Li, Mingchao, et al.
Publicado: (2021)

Network Pharmacology Approach to Uncover the Mechanism Governing the Effect of Simiao Powder on Knee Osteoarthritis
por: Huang, Zhengquan, et al.
Publicado: (2020)

Characteristics of sensory innervation in synovium of rats within different knee osteoarthritis models and the correlation between synovial fibrosis and hyperalgesia
por: Zhang, Li, et al.
Publicado: (2021)

MicroRNA-10a-3p Improves Cartilage Degeneration by Regulating CH25H-CYP7B1-RORα Mediated Cholesterol Metabolism in Knee Osteoarthritis Rats
por: Li, Xiaochen, et al.
Publicado: (2021)

Vanillic Acid Reduces Pain-Related Behavior in Knee Osteoarthritis Rats Through the Inhibition of NLRP3 Inflammasome-Related Synovitis
por: Ma, Zhenyuan, et al.
Publicado: (2021)

Interventional effects of the direct application of “Sanse powder” on knee osteoarthritis in rats as determined from lipidomics via UPLC-Q-Exactive Orbitrap MS
por: Wu, Peng, et al.
Publicado: (2020)

Relationship between the pyroptosis of fibroblast-like synoviocytes and HMGB1 secretion in knee osteoarthritis
por: Xiao, Yancheng, et al.
Publicado: (2021)

l-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway
por: Liao, Taiyang, et al.
Publicado: (2023)

Chrysin ameliorates synovitis and fibrosis of osteoarthritic fibroblast-like synoviocytes in rats through PERK/TXNIP/NLRP3 signaling
por: Ding, Liang, et al.
Publicado: (2023)

Targeting NLRP3 Inflammasome Alleviates Synovitis by Reducing Pyroptosis in Rats with Experimental Temporomandibular Joint Osteoarthritis
por: Xin, Yinzi, et al.
Publicado: (2022)

Effect of Ultrasound-Enhanced Transdermal Drug Delivery Efficiency of Nanoparticles and Brucine
por: Zhang, Nongshan, et al.
Publicado: (2017)

Network Pharmacology Approach to Uncover the Mechanism Governing the Effect of Radix Achyranthis Bidentatae on Osteoarthritis
por: Zhang, Laigen, et al.
Publicado: (2020)

Icariin alleviates osteoarthritis by inhibiting NLRP3-mediated pyroptosis
por: Zu, Yan, et al.
Publicado: (2019)

Resatorvid alleviates experimental inflammatory TMJOA by restraining chondrocyte pyroptosis and synovial inflammation
por: Liu, Xin, et al.
Publicado: (2023)

GCTOF-MS Combined LC-QTRAP-MS/MS Reveals Metabolic Difference Between Osteoarthritis and Osteoporotic Osteoarthritis and the Intervention Effect of Erxian Decoction
por: Ma, Zhenyuan, et al.
Publicado: (2022)

Acupotomy Improves Synovial Hypoxia, Synovitis and Angiogenesis in KOA Rabbits
por: Guo, Yan, et al.
Publicado: (2023)

Effects of synovial macrophages in osteoarthritis
por: Zhao, Kun, et al.
Publicado: (2023)

Chrysin Attenuates the NLRP3 Inflammasome Cascade to Reduce Synovitis and Pain in KOA Rats
por: Liao, Taiyang, et al.
Publicado: (2020)

Increased synovial lipodystrophy induced by high fat diet aggravates synovitis in experimental osteoarthritis
por: Larrañaga-Vera, Ane, et al.
Publicado: (2017)

Synovial Fluid in Knee Osteoarthritis Extends Proinflammatory Niche for Macrophage Polarization
por: Kulkarni, Priya, et al.
Publicado: (2022)

Profiling of inflammatory mediators in the synovial fluid related to pain in knee osteoarthritis
por: Li, Li, et al.
Publicado: (2020)

Baicalein alleviates osteoarthritis by protecting subchondral bone, inhibiting angiogenesis and synovial proliferation
por: Li, Bin, et al.
Publicado: (2021)

Serum and synovial fluid lipidomic profiles predict obesity-associated osteoarthritis, synovitis, and wound repair
por: Wu, Chia-Lung, et al.
Publicado: (2017)

Ginsenoside compound K alleviates osteoarthritis by inhibiting NLRP3‑mediated pyroptosis
por: Li, Yuguo, et al.
Publicado: (2023)

Combination of magnesium ions and vitamin C alleviates synovitis and osteophyte formation in osteoarthritis of mice
por: Yao, Hao, et al.
Publicado: (2020)

The association between patellofemoral grind and synovitis in knee osteoarthritis: data from the osteoarthritis initiative
por: Deng, Hui, et al.
Publicado: (2023)

Effect of intramedullary nail and locking plate in the treatment of proximal humerus fracture: an update systematic review and meta-analysis
por: Shi, Xiaoqing, et al.
Publicado: (2019)

Clinical Lecture on Synovitis and Granular Disease of the Synovial Membrane— Pulpy Degeneration; Scrofulous Synovitis
por: Macnamara, C.
Publicado: (1879)

Monotropein attenuates apoptosis and pyroptosis in chondrocytes and alleviates osteoarthritis progression in mice
por: Li, Zhen, et al.
Publicado: (2023)

Synovial Fluid Macrophage Migration Inhibitory Factor Levels Correlate with Severity of Self-Reported Pain in Knee Osteoarthritis Patients
por: Zhang, Pei-liang, et al.
Publicado: (2016)

Correlation between systemic markers of inflammation and local synovitis in knee osteoarthritis
por: Babaei, Mansour, et al.
Publicado: (2019)

The histopathological synovitis score is influenced by biopsy location in patients with knee osteoarthritis
por: Mussawy, Haider, et al.
Publicado: (2021)

Immunoregulation of synovial macrophages for the treatment of osteoarthritis
por: Xu, Mingze, et al.
Publicado: (2023)

Synovitis Ointment Improved Knee Osteoarthritis by Suppressing SDF-1/CXCR4 Signaling Pathway
por: Zhang, Jin, et al.
Publicado: (2022)

Mechanism of NLRP3 inflammasome intervention for synovitis in knee osteoarthritis: A review of TCM intervention
por: Han, Xianfu, et al.
Publicado: (2023)

Traumatic Synovitis of the Knee
Publicado: (1907)

Cannot write session to /tmp/vufind_sessions/sess_0cs0dvta2av1dioknb9d8jn210