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MHC Class I Molecules Exacerbate Viral Infection by Disrupting Type I Interferon Signaling

MHC class I molecules are key in the presentation of antigen and initiation of adaptive CD8+ T cell responses. In addition to its classical activity, MHC I may possess nonclassical functions. We have previously identified a regulatory role of MHC I in TLR signaling and antibacterial immunity. Howeve...

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Detalles Bibliográficos
Autores principales:	Xia, Simo, Tao, Yijie, Cui, Likun, Yu, Yizhi, Xu, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754968/ https://www.ncbi.nlm.nih.gov/pubmed/31583257 http://dx.doi.org/10.1155/2019/5370706

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