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Wnt1 Promotes EAAT2 Expression and Mediates the Protective Effects of Astrocytes on Dopaminergic Cells in Parkinson's Disease

BACKGROUND: Wnt/β-catenin signaling has been reported to exert cytoprotective effects in a cellular model of Parkinson's disease (PD). Glutamate excitotoxicity has been suggested to contribute to the pathogenesis of PD, and excitatory amino acid transporters (EAATs) play a predominant role in c...

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Detalles Bibliográficos
Autores principales: Wei, Lei, Chen, Chuan, Ding, Li, Mo, Mingshu, Zou, Jing, Lu, Zhenze, Li, Haiyan, Wu, Haotian, Dai, Yongqiang, Xu, Pingyi, Lu, Zhengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754970/
https://www.ncbi.nlm.nih.gov/pubmed/31582965
http://dx.doi.org/10.1155/2019/1247276