SIRT6 transcriptionally regulates global protein synthesis through transcription factor Sp1 independent of its deacetylase activity

Global protein synthesis is emerging as an important player in the context of aging and age-related diseases. However, the intricate molecular networks that regulate protein synthesis are poorly understood. Here, we report that SIRT6, a nuclear-localized histone deacetylase represses global protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Ravi, Venkatraman, Jain, Aditi, Khan, Danish, Ahamed, Faiz, Mishra, Sneha, Giri, Malyasree, Inbaraj, Meena, Krishna, Swati, Sarikhani, Mohsen, Maity, Sangeeta, Kumar, Shweta, Shah, Riyaz Ahmad, Dave, Pratik, Pandit, Anwit S, Rajendran, Rajprabu, Desingu, Perumal A, Varshney, Umesh, Das, Saumitra, Kolthur-Seetharam, Ullas, Rajakumari, Sona, Singh, Mahavir, Sundaresan, Nagalingam R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755095/
https://www.ncbi.nlm.nih.gov/pubmed/31372634
http://dx.doi.org/10.1093/nar/gkz648

Ejemplares similares

Ejemplares similares