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Structure of the primed state of the ATPase domain of chromatin remodeling factor ISWI bound to the nucleosome

ATP-dependent chromatin remodeling factors of SWI/SNF2 family including ISWI, SNF2, CHD1 and INO80 subfamilies share a conserved but functionally non-interchangeable ATPase domain. Here we report cryo-electron microscopy (cryo-EM) structures of the nucleosome bound to an ISWI fragment with deletion...

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Detalles Bibliográficos
Autores principales: Chittori, Sagar, Hong, Jingjun, Bai, Yawen, Subramaniam, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755096/
https://www.ncbi.nlm.nih.gov/pubmed/31402386
http://dx.doi.org/10.1093/nar/gkz670

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