Cargando…

A 212-nt long RNA structure in the Tobacco necrosis virus-D RNA genome is resistant to Xrn degradation

Plus-strand RNA viruses can accumulate viral RNA degradation products during infections. Some of these decay intermediates are generated by the cytosolic 5′-to-3′ exoribonuclease Xrn1 (mammals and yeast) or Xrn4 (plants) and are formed when the enzyme stalls on substrate RNAs upon encountering inhib...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gunawardene, Chaminda D, Newburn, Laura R, White, K Andrew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	RNA and RNA-protein complexes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755097/ https://www.ncbi.nlm.nih.gov/pubmed/31392982 http://dx.doi.org/10.1093/nar/gkz668

Ejemplares similares

A low-complexity region in human XRN1 directly recruits deadenylation and decapping factors in 5′–3′ messenger RNA decay
por: Chang, Chung-Te, et al.
Publicado: (2019)

Xrn1p acts at multiple steps in the budding-yeast RNAi pathway to enhance the efficiency of silencing
por: Getz, Matthew A, et al.
Publicado: (2020)

Determinants of the temperature adaptation of mRNA degradation
por: Jaquet, Vincent, et al.
Publicado: (2022)

N-terminal residues of human dyskerin are required for interactions with telomerase RNA that prevent RNA degradation
por: MacNeil, Deanna E, et al.
Publicado: (2019)

Activation of viral transcription by stepwise largescale folding of an RNA virus genome
por: Chkuaseli, Tamari, et al.
Publicado: (2020)

Role of ribosome assembly in Escherichia coli ribosomal RNA degradation
por: Jain, Chaitanya
Publicado: (2018)

Transcription feedback dynamics in the wake of cytoplasmic mRNA degradation shutdown
por: Chappleboim, Alon, et al.
Publicado: (2022)

Dimerization of an umbravirus RNA genome activates subgenomic mRNA transcription
por: Chkuaseli, Tamari, et al.
Publicado: (2023)

A multidisciplinary approach to the identification of the protein–RNA connectome in double-stranded RNA virus capsids
por: Sung, Po-yu, et al.
Publicado: (2023)

Probing of RNA structures in a positive sense RNA virus reveals selection pressures for structural elements
por: Watters, Kyle E, et al.
Publicado: (2018)

A conserved RNA structure is essential for a satellite RNA-mediated inhibition of helper virus accumulation
por: He, Lu, et al.
Publicado: (2019)

Compositional complementarity between genomic RNA and coat proteins in positive-sense single-stranded RNA viruses
por: Adlhart, Marlene, et al.
Publicado: (2022)

Structural and kinetic insights into stimulation of RppH-dependent RNA degradation by the metabolic enzyme DapF
por: Gao, Ang, et al.
Publicado: (2018)

SERRATE interacts with the nuclear exosome targeting (NEXT) complex to degrade primary miRNA precursors in Arabidopsis
por: Bajczyk, Mateusz, et al.
Publicado: (2020)

Structural and phenotypic analysis of Chikungunya virus RNA replication elements
por: Kendall, Catherine, et al.
Publicado: (2019)

Polynucleotide phosphorylase promotes the stability and function of Hfq-binding sRNAs by degrading target mRNA-derived fragments
por: Cameron, Todd A, et al.
Publicado: (2019)

miR-122, small RNA annealing and sequence mutations alter the predicted structure of the Hepatitis C virus 5′ UTR RNA to stabilize and promote viral RNA accumulation
por: Amador-Cañizares, Yalena, et al.
Publicado: (2018)

Sequential disruption of SPLASH-identified vRNA–vRNA interactions challenges their role in influenza A virus genome packaging
por: Jakob, Celia, et al.
Publicado: (2023)

Parentally inherited long non-coding RNA Cyrano is involved in zebrafish neurodevelopment
por: Sarangdhar, Mayuresh Anant, et al.
Publicado: (2018)

Identification of the RNA polymerase I-RNA interactome
por: Piñeiro, David, et al.
Publicado: (2018)

The intrinsically disordered N-terminal arm of the brome mosaic virus coat protein specifically recognizes the RNA motif that directs the initiation of viral RNA replication
por: Jacobs, Alexander, et al.
Publicado: (2018)

Synthesis of RNA-cofactor conjugates and structural exploration of RNA recognition by an m(6)A RNA methyltransferase
por: Meynier, Vincent, et al.
Publicado: (2022)

SUMOylation of YTHDF2 promotes mRNA degradation and cancer progression by increasing its binding affinity with m(6)A-modified mRNAs
por: Hou, Guofang, et al.
Publicado: (2021)

Small RNA profiling in Chlamydomonas: insights into chloroplast RNA metabolism
por: Cavaiuolo, Marina, et al.
Publicado: (2017)

Investigating RNA–RNA interactions through computational and biophysical analysis
por: Mrozowich, Tyler, et al.
Publicado: (2023)

Positive-sense RNA viruses reveal the complexity and dynamics of the cellular and viral epitranscriptomes during infection
por: McIntyre, Will, et al.
Publicado: (2018)

An unexpected RNA distal interaction mode found in an essential region of the hepatitis C virus genome
por: Cantero-Camacho, Ángel, et al.
Publicado: (2018)

DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA
por: Awasthi, Sharad, et al.
Publicado: (2018)

A unique internal ribosome entry site representing a dynamic equilibrium state of RNA tertiary structure in the 5′-UTR of Wheat yellow mosaic virus RNA1
por: Geng, Guowei, et al.
Publicado: (2020)

The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis
por: Nguyen, Tuan M, et al.
Publicado: (2020)

Functional organization of box C/D RNA-guided RNA methyltransferase
por: Yang, Zuxiao, et al.
Publicado: (2020)

Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH
por: Gao, Ang, et al.
Publicado: (2020)

sRNA-mediated RNA processing regulates bacterial cell division
por: Grützner, Julian, et al.
Publicado: (2021)

Role of NS2 specific RNA binding and phosphorylation in liquid–liquid phase separation and virus assembly
por: Rahman, Shah Kamranur, et al.
Publicado: (2022)

RNA interactome capture in Escherichia coli globally identifies RNA-binding proteins
por: Stenum, Thomas Søndergaard, et al.
Publicado: (2023)

Multiple RNA–RNA tertiary interactions are dispensable for formation of a functional U2/U6 RNA catalytic core in the spliceosome
por: Bao, Penghui, et al.
Publicado: (2018)

Endogenous piRNA-guided slicing triggers responder and trailer piRNA production from viral RNA in Aedes aegypti mosquitoes
por: Joosten, Joep, et al.
Publicado: (2021)

When translation elongation is impaired, the mRNA is uniformly destabilized by the RNA degradosome, while the concentration of mRNA is altered along the molecule
por: Duviau, Marie-Pierre, et al.
Publicado: (2023)

The RNA export factor TbMex67 connects transcription and RNA export in Trypanosoma brucei and sets boundaries for RNA polymerase I
por: Pozzi, Berta, et al.
Publicado: (2023)

Computational analysis of ribonomics datasets identifies long non-coding RNA targets of γ-herpesviral miRNAs
por: Sethuraman, Sunantha, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_917iiul6hlg9s0g5fl48brl9tm