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Extracellular annexin-A1 promotes myeloid/granulocytic differentiation of hematopoietic stem/progenitor cells via the Ca(2+)/MAPK signalling transduction pathway

Annexin A1 (AnxA1) modulates neutrophil life span and bone marrow/blood cell trafficking thorough activation of formyl-peptide receptors (FPRs). Here, we investigated the effect of exogenous AnxA1 on haematopoiesis in the mouse. Treatment of C57BL/6 mice with recombinant AnxA1 (rAnxA1) reduced the g...

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Detalles Bibliográficos
Autores principales:	Barbosa, Christiano M. V., Fock, Ricardo Ambrósio, Hastreiter, Araceli Aparecida, Reutelingsperger, Cris, Perretti, Mauro, Paredes-Gamero, Edgar J., Farsky, Sandra H. P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755131/ https://www.ncbi.nlm.nih.gov/pubmed/31552142 http://dx.doi.org/10.1038/s41420-019-0215-1

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