Protein kinase C inhibitors override ZEB1-induced chemoresistance in HCC

Epithelial–mesenchymal transition (EMT) is a process by which tumour cells lose epithelial characteristics, become mesenchymal and highly motile. EMT pathways also induce stem cell features and resistance to apoptosis. Identifying and targeting this pool of tumour cells is a major challenge. Protein...

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Detalles Bibliográficos
Autores principales: Sreekumar, Rahul, Emaduddin, Muhammad, Al-Saihati, Hajir, Moutasim, Karwan, Chan, James, Spampinato, Marcello, Bhome, Rahul, Yuen, Ho Ming, Mescoli, Claudia, Vitale, Alessandro, Cillo, Umberto, Rugge, Massimo, Primrose, John, Hilal, Mohammad Abu, Thirdborough, Stephen, Tulchinsky, Eugene, Thomas, Gareth, Mirnezami, Alex, Sayan, A. Emre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755133/
https://www.ncbi.nlm.nih.gov/pubmed/31543517
http://dx.doi.org/10.1038/s41419-019-1885-6

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