Cargando…

TGF-β induces periodontal ligament stem cell senescence through increase of ROS production

Periodontal ligament stem cells (PDLSCs) are vital for the regeneration of periodontal tissue. Transforming growth factor (TGF) β1, a potent stimulator of tissue regeneration, is extensive and abundant in the bone matrix. However, the effect of TGF-β1 in periodontal differentiation remains to be elu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Chun, Ji, Qiuxia, Zhang, Chunyang, Xu, Shuo, Sun, Hui, Li, Zhiyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755147/ https://www.ncbi.nlm.nih.gov/pubmed/31432132 http://dx.doi.org/10.3892/mmr.2019.10580

Ejemplares similares

TGF-β1 induces senescence of bone marrow mesenchymal stem cells via increase of mitochondrial ROS production
por: Wu, Junfang, et al.
Publicado: (2014)

Effect of FGF-2, TGF-β-1, and BMPs on Teno/Ligamentogenesis and Osteo/Cementogenesis of Human Periodontal Ligament Stem Cells
por: Hyun, Sun-Yi, et al.
Publicado: (2017)

Premature Senescence and Increased TGFβ Signaling in the Absence of Tgif1
por: Zerlanko, Brad J., et al.
Publicado: (2012)

Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue
por: Ikegami, Kuniko, et al.
Publicado: (2023)

Allogeneic Periodontal Ligament Stem Cell Therapy for Periodontitis in Swine
por: Ding, Gang, et al.
Publicado: (2010)

Transforming Growth Factor-β3/Chitosan Sponge (TGF-β3/CS) Facilitates Osteogenic Differentiation of Human Periodontal Ligament Stem Cells
por: Li, Yangfan, et al.
Publicado: (2019)

Dexamethasone Induces Senescence-Associated Changes in Trabecular Meshwork Cells by Increasing ROS Levels Via the TGFβ/Smad3-NOX4 Axis
por: Li, Haijun, et al.
Publicado: (2023)

Loss of IκB kinase β promotes myofibroblast transformation and senescence through activation of the ROS-TGFβ autocrine loop
por: Chen, Liang, et al.
Publicado: (2016)

Senescent Markers Expressed by Periodontal Ligament-Derived Stem Cells (PDLSCs) Harvested from Patients with Periodontitis Can Be Rejuvenated by RG108
por: Roato, Ilaria, et al.
Publicado: (2023)

Periodontal tissue stem cells and mesenchymal stem cells in the periodontal ligament()
por: Iwayama, Tomoaki, et al.
Publicado: (2022)

TGFβ1 Induces Senescence and Attenuated VEGF Production in Retinal Pericytes
por: Avramovic, Dragana, et al.
Publicado: (2022)

Asiaticoside delays senescence and attenuate generation of ROS in UV‑exposure cells through regulates TGF‑β1/Smad pathway
por: Jiang, Honghao, et al.
Publicado: (2022)

TGF-β induces corneal endothelial senescence via increase of mitochondrial reactive oxygen species in chronic corneal allograft failure
por: Li, Zhiyuan, et al.
Publicado: (2018)

Advanced glycosylated end products restrain the osteogenic differentiation of the periodontal ligament stem cell
por: Guo, Zhu-Ling, et al.
Publicado: (2019)

Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis
por: Chen, Qin, et al.
Publicado: (2021)

Golgin Subfamily A Member 5 Is Essential for Production of Extracellular Matrix Proteins during TGF-β1-Induced Periodontal Ligament-Fibroblastic Differentiation
por: Kim, Hyun-Jin, et al.
Publicado: (2022)

TGF-β3 Induces Autophagic Activity by Increasing ROS Generation in a NOX4-Dependent Pathway
por: Zhang, Yun, et al.
Publicado: (2019)

NADPH-dependent ROS accumulation contributes to the impaired osteogenic differentiation of periodontal ligament stem cells under high glucose conditions
por: Zhang, Yi-lin, et al.
Publicado: (2023)

ROS and TGFβ: from pancreatic tumour growth to metastasis
por: Chang, Chao-Hui, et al.
Publicado: (2021)

Therapeutic potential of periodontal ligament stem cells
por: Queiroz, Aline, et al.
Publicado: (2021)

Regulation of self-renewal and senescence in primitive mesenchymal stem cells by Wnt and TGFβ signaling
por: Mazzella, Matteo, et al.
Publicado: (2023)

Macrophage polarization in periodontal ligament stem cells enhanced periodontal regeneration
por: Liu, Jiaying, et al.
Publicado: (2019)

Activated Yes-Associated Protein Accelerates Cell Cycle, Inhibits Apoptosis, and Delays Senescence in Human Periodontal Ligament Stem Cells
por: Jia, Linglu, et al.
Publicado: (2018)

MEST Regulates the Stemness of Human Periodontal Ligament Stem Cells
por: Hasegawa, Daigaku, et al.
Publicado: (2020)

Induction of senescence in primary glioblastoma cells by serum and TGFβ
por: Kumar, Ritesh, et al.
Publicado: (2017)

TGF-β Signaling in Cellular Senescence and Aging-Related Pathology
por: Tominaga, Kana, et al.
Publicado: (2019)

Periodontal Ligament Stem Cells in the Periodontitis Microenvironment Are Sensitive to Static Mechanical Strain
por: Liu, Jia, et al.
Publicado: (2017)

Promise of periodontal ligament stem cells in regeneration of periodontium
por: Maeda, Hidefumi, et al.
Publicado: (2011)

Periodontal Ligament Stem Cells Regulate Apoptosis of Neutrophils
por: Wang, Qing, et al.
Publicado: (2017)

Mass acquisition of human periodontal ligament stem cells
por: Maeda, Hidefumi
Publicado: (2020)

Impact of Magnetic Stimulation on Periodontal Ligament Stem Cells
por: Peluso, Valentina, et al.
Publicado: (2021)

Study of platelet‐rich fibrin combined with rat periodontal ligament stem cells in periodontal tissue regeneration
por: Duan, Xuejing, et al.
Publicado: (2018)

Comparison of Osteoblastic Differentiation of Human Periodontal Ligament Stem Cells through Application of Two β-tricalcium Phosphate Products: An in vitro Study
por: Mirkhani, Seyed Mohammad Hossein, et al.
Publicado: (2022)

IL-1β and TNF-α suppress TGF-β-promoted NGF expression in periodontal ligament-derived fibroblasts through inactivation of TGF-β-induced Smad2/3- and p38 MAPK-mediated signals
por: Ohta, Maiko, et al.
Publicado: (2018)

Otic Neurogenesis Is Regulated by TGFβ in a Senescence-Independent Manner
por: Magariños, Marta, et al.
Publicado: (2020)

Periodontitis promotes the proliferation and suppresses the differentiation potential of human periodontal ligament stem cells
por: ZHENG, WEI, et al.
Publicado: (2015)

Enhancement of periodontal tissue regeneration by transplantation of osteoprotegerin-engineered periodontal ligament stem cells
por: Su, Fang, et al.
Publicado: (2015)

Evaluation of the periodontal regenerative properties of patterned human periodontal ligament stem cell sheets
por: Kim, Joong-Hyun, et al.
Publicado: (2017)

The Fate of Transplanted Periodontal Ligament Stem Cells in Surgically Created Periodontal Defects in Rats
por: Iwasaki, Kengo, et al.
Publicado: (2019)

MicroRNA-133b targets TGFβ receptor I to inhibit TGF-β-induced epithelial-to-mesenchymal transition and metastasis by suppressing the TGF-β/SMAD pathway in breast cancer
por: WANG, SHENGJIE, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9k6kd1dclci64an1lltpuf2pg9