DNA-PKcs PARylation regulates DNA-PK kinase activity in the DNA damage response

DNA-dependent protein kinase catalytic subunit (-PKcs) is the core protein involved in the non-homologous end-joining repair of double-strand breaks. In addition, it can form a complex with poly(ADP-ribose) polymerase 1 (PARP1), which catalyzes protein PARylation. However, it is unclear how DNA-PKcs...

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Detalles Bibliográficos
Autores principales: Han, Yang, Jin, Feng, Xie, Ying, Liu, Yike, Hu, Sai, Liu, Xiao-Dan, Guan, Hua, Gu, Yongqing, Ma, Teng, Zhou, Ping-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755157/
https://www.ncbi.nlm.nih.gov/pubmed/31485633
http://dx.doi.org/10.3892/mmr.2019.10640

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755157/
https://www.ncbi.nlm.nih.gov/pubmed/31485633
http://dx.doi.org/10.3892/mmr.2019.10640

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