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SREBP2 is upregulated in esophageal squamous cell carcinoma and co-operates with c-Myc to regulate HMGCR expression

Dysregulations of the mevalonate pathway (MVA) have been previously identified. Our previous study demonstrated that 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), the rate-limiting enzyme of the MVA pathway, was upregulated in esophageal squamous cell carcinoma (ESCC) and statin-inhibited...

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Detalles Bibliográficos
Autores principales:	Zhong, Chenxi, Fan, Limin, Li, Zhigang, Yao, Feng, Zhao, Heng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755167/ https://www.ncbi.nlm.nih.gov/pubmed/31432128 http://dx.doi.org/10.3892/mmr.2019.10577

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