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Homoharringtonine enhances the effect of imatinib on chronic myelogenous leukemia cells by downregulating ZFX
Homoharringtonine (HHT) and imatinib have a synergistic effect in the clinical treatment of chronic myeloid leukemia (CML). The purpose of the present study was to explore the underlying mechanisms by which HHT enhanced imatinib sensitivity. K562 CML cells were treated with HHT and imatinib separate...
Autores principales: | Wu, Jingjing, Wei, Bin, Shi, Yuye, Lu, Xueying, Ding, Yihan, Wang, Chunling, Li, Yufeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755169/ https://www.ncbi.nlm.nih.gov/pubmed/31432109 http://dx.doi.org/10.3892/mmr.2019.10539 |
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