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Hepatic NPC1L1 overexpression attenuates alcoholic autophagy in mice

Alcohol consumption causes liver steatosis in humans. Metabolic disorders of lipids are one of the factors that cause liver steatosis in hepatocytes. Hepatic Niemann-Pick C1-like 1 (NPC1L1) regulates lipid homeostasis in mammals. The relationship between NPC1L1 and autophagy in those with a history...

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Detalles Bibliográficos
Autores principales: Wang, Youlin, Yang, Pan, Zhang, Bo, Ding, Yao, Lei, Shun, Hou, Yuning, Guan, Xiaoqing, Li, Qingwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755247/
https://www.ncbi.nlm.nih.gov/pubmed/31432115
http://dx.doi.org/10.3892/mmr.2019.10549

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