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Piperine ameliorates the severity of fibrosis via inhibition of TGF-β/SMAD signaling in a mouse model of chronic pancreatitis

Chronic pancreatitis (CP) is characterized by recurrent pancreatic injury, resulting in inflammation and fibrosis. Currently, there are no drugs for the treatment of pancreatic fibrosis associated with CP. Piperine, a natural alkaloid found in black pepper, has been reported to show anti-inflammator...

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Detalles Bibliográficos
Autores principales: Choi, Ji-Won, Lee, Sung-Kon, Kim, Myoung-Jin, Kim, Dong-Gu, Shin, Joon-Yeon, Zhou, Ziqi, Jo, Il-Joo, Song, Ho-Joon, Bae, Gi-Sang, Park, Sung-Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755249/
https://www.ncbi.nlm.nih.gov/pubmed/31485676
http://dx.doi.org/10.3892/mmr.2019.10635