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Piperine ameliorates the severity of fibrosis via inhibition of TGF-β/SMAD signaling in a mouse model of chronic pancreatitis
Chronic pancreatitis (CP) is characterized by recurrent pancreatic injury, resulting in inflammation and fibrosis. Currently, there are no drugs for the treatment of pancreatic fibrosis associated with CP. Piperine, a natural alkaloid found in black pepper, has been reported to show anti-inflammator...
Autores principales: | Choi, Ji-Won, Lee, Sung-Kon, Kim, Myoung-Jin, Kim, Dong-Gu, Shin, Joon-Yeon, Zhou, Ziqi, Jo, Il-Joo, Song, Ho-Joon, Bae, Gi-Sang, Park, Sung-Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755249/ https://www.ncbi.nlm.nih.gov/pubmed/31485676 http://dx.doi.org/10.3892/mmr.2019.10635 |
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