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Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy
A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cance...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755298/ https://www.ncbi.nlm.nih.gov/pubmed/31611927 http://dx.doi.org/10.1155/2019/5216346 |
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author | Mkango, Sara B. Shaban, Nyimvua Mureithi, Eunice Ngoma, Twalib |
author_facet | Mkango, Sara B. Shaban, Nyimvua Mureithi, Eunice Ngoma, Twalib |
author_sort | Mkango, Sara B. |
collection | PubMed |
description | A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of the combined radiotherapy and chemotherapy as a way to treat breast cancer, and different treatment approaches are incorporated into the model. Also, the model is fitted to data on patients with breast cancer in Tanzania. We determine new treatment strategies, and finally, we show that when sufficient amount of chemotherapy and radiotherapy with a low decay rate is used, the drug will be significantly more effective in combating the disease while health cells remain above the threshold. |
format | Online Article Text |
id | pubmed-6755298 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-67552982019-10-14 Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy Mkango, Sara B. Shaban, Nyimvua Mureithi, Eunice Ngoma, Twalib Comput Math Methods Med Research Article A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of the combined radiotherapy and chemotherapy as a way to treat breast cancer, and different treatment approaches are incorporated into the model. Also, the model is fitted to data on patients with breast cancer in Tanzania. We determine new treatment strategies, and finally, we show that when sufficient amount of chemotherapy and radiotherapy with a low decay rate is used, the drug will be significantly more effective in combating the disease while health cells remain above the threshold. Hindawi 2019-09-11 /pmc/articles/PMC6755298/ /pubmed/31611927 http://dx.doi.org/10.1155/2019/5216346 Text en Copyright © 2019 Sara B. Mkango et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Mkango, Sara B. Shaban, Nyimvua Mureithi, Eunice Ngoma, Twalib Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy |
title | Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy |
title_full | Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy |
title_fullStr | Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy |
title_full_unstemmed | Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy |
title_short | Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy |
title_sort | dynamics of breast cancer under different rates of chemoradiotherapy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755298/ https://www.ncbi.nlm.nih.gov/pubmed/31611927 http://dx.doi.org/10.1155/2019/5216346 |
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