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Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy

A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cance...

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Autores principales: Mkango, Sara B., Shaban, Nyimvua, Mureithi, Eunice, Ngoma, Twalib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755298/
https://www.ncbi.nlm.nih.gov/pubmed/31611927
http://dx.doi.org/10.1155/2019/5216346
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author Mkango, Sara B.
Shaban, Nyimvua
Mureithi, Eunice
Ngoma, Twalib
author_facet Mkango, Sara B.
Shaban, Nyimvua
Mureithi, Eunice
Ngoma, Twalib
author_sort Mkango, Sara B.
collection PubMed
description A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of the combined radiotherapy and chemotherapy as a way to treat breast cancer, and different treatment approaches are incorporated into the model. Also, the model is fitted to data on patients with breast cancer in Tanzania. We determine new treatment strategies, and finally, we show that when sufficient amount of chemotherapy and radiotherapy with a low decay rate is used, the drug will be significantly more effective in combating the disease while health cells remain above the threshold.
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spelling pubmed-67552982019-10-14 Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy Mkango, Sara B. Shaban, Nyimvua Mureithi, Eunice Ngoma, Twalib Comput Math Methods Med Research Article A type of cancer which originates from the breast tissue is referred to as breast cancer. Globally, it is the most common cause of death in women. Treatments such as radiotherapy, chemotherapy, hormone therapy, immunotherapy, and gene therapy are the main strategies in the fight against breast cancer. The present study aims at investigating the effects of the combined radiotherapy and chemotherapy as a way to treat breast cancer, and different treatment approaches are incorporated into the model. Also, the model is fitted to data on patients with breast cancer in Tanzania. We determine new treatment strategies, and finally, we show that when sufficient amount of chemotherapy and radiotherapy with a low decay rate is used, the drug will be significantly more effective in combating the disease while health cells remain above the threshold. Hindawi 2019-09-11 /pmc/articles/PMC6755298/ /pubmed/31611927 http://dx.doi.org/10.1155/2019/5216346 Text en Copyright © 2019 Sara B. Mkango et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mkango, Sara B.
Shaban, Nyimvua
Mureithi, Eunice
Ngoma, Twalib
Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy
title Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy
title_full Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy
title_fullStr Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy
title_full_unstemmed Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy
title_short Dynamics of Breast Cancer under Different Rates of Chemoradiotherapy
title_sort dynamics of breast cancer under different rates of chemoradiotherapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755298/
https://www.ncbi.nlm.nih.gov/pubmed/31611927
http://dx.doi.org/10.1155/2019/5216346
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