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Pax4 synergistically acts with Pdx1, Ngn3 and MafA to induce HuMSCs to differentiate into functional pancreatic β-cells

It has been indicated that the combination of pancreatic and duodenal homeobox 1 (Pdx1), MAF bZIP transcription factor A (MafA) and neurogenin 3 (Ngn3) was able to reprogram various cell types towards pancreatic β-like cells (pβLCs). Paired box 4 (Pax4), a transcription factor, has a key role in reg...

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Detalles Bibliográficos
Autores principales:	Zhang, Ting, Wang, Hongwu, Wang, Tianyou, Wei, Chiju, Jiang, Hui, Jiang, Shayi, Yang, Jingwei, Shao, Jingbo, Ma, Lian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755441/ https://www.ncbi.nlm.nih.gov/pubmed/31572507 http://dx.doi.org/10.3892/etm.2019.7854

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