GSK343 induces autophagy and downregulates the AKT/mTOR signaling pathway in pancreatic cancer cells

Pancreatic cancer is a common malignancy that has a poor prognosis and limited therapeutic options. Enhancer of zeste homolog 2 (EZH2) serves a key role in the progression of different types of cancers. The effect of GSK343 (a competitive inhibitor of EZH2) on pancreatic cancer cells was assessed in...

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Detalles Bibliográficos
Autores principales: Xu, Hao, Zhang, Linshi, Qian, Xiaohui, Zhou, Xiaohu, Yan, Yingcai, Zhou, Jiarong, Ge, Wenhao, Albahde, Mugahed, Wang, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755448/
https://www.ncbi.nlm.nih.gov/pubmed/31572509
http://dx.doi.org/10.3892/etm.2019.7845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755448/
https://www.ncbi.nlm.nih.gov/pubmed/31572509
http://dx.doi.org/10.3892/etm.2019.7845

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