Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019)

In article number 1900865, Ke Xu and co‐workers report, through super‐resolution microscopy, an unexpected, fast degradation pathway of the vimentin cytoskeletal system under hypo‐osmotic stress. Together with calcium imaging and biochemical analysis, the study further unveils that this degradation...

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Autores principales: Pan, Leiting, Zhang, Ping, Hu, Fen, Yan, Rui, He, Manni, Li, Wan, Xu, Jingjun, Xu, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Back Cover
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755515/
http://dx.doi.org/10.1002/advs.201970112
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author Pan, Leiting
Zhang, Ping
Hu, Fen
Yan, Rui
He, Manni
Li, Wan
Xu, Jingjun
Xu, Ke
author_facet Pan, Leiting
Zhang, Ping
Hu, Fen
Yan, Rui
He, Manni
Li, Wan
Xu, Jingjun
Xu, Ke
author_sort Pan, Leiting
collection PubMed
description In article number 1900865, Ke Xu and co‐workers report, through super‐resolution microscopy, an unexpected, fast degradation pathway of the vimentin cytoskeletal system under hypo‐osmotic stress. Together with calcium imaging and biochemical analysis, the study further unveils that this degradation is due to proteolysis by the calcium‐dependent protease calpain, activated by hypotonic stress‐induced calcium release from intracellular stores. [Image: see text]
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spelling pubmed-67555152019-09-26 Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019) Pan, Leiting Zhang, Ping Hu, Fen Yan, Rui He, Manni Li, Wan Xu, Jingjun Xu, Ke Adv Sci (Weinh) Back Cover In article number 1900865, Ke Xu and co‐workers report, through super‐resolution microscopy, an unexpected, fast degradation pathway of the vimentin cytoskeletal system under hypo‐osmotic stress. Together with calcium imaging and biochemical analysis, the study further unveils that this degradation is due to proteolysis by the calcium‐dependent protease calpain, activated by hypotonic stress‐induced calcium release from intracellular stores. [Image: see text] John Wiley and Sons Inc. 2019-09-18 /pmc/articles/PMC6755515/ http://dx.doi.org/10.1002/advs.201970112 Text en © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Back Cover
Pan, Leiting
Zhang, Ping
Hu, Fen
Yan, Rui
He, Manni
Li, Wan
Xu, Jingjun
Xu, Ke
Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019)
title Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019)
title_full Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019)
title_fullStr Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019)
title_full_unstemmed Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019)
title_short Super‐Resolution Microscopy: Hypotonic Stress Induces Fast, Reversible Degradation of the Vimentin Cytoskeleton via Intracellular Calcium Release (Adv. Sci. 18/2019)
title_sort super‐resolution microscopy: hypotonic stress induces fast, reversible degradation of the vimentin cytoskeleton via intracellular calcium release (adv. sci. 18/2019)
topic Back Cover
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755515/
http://dx.doi.org/10.1002/advs.201970112
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