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Recombinant Sj16 protein with novel activity alleviates hepatic granulomatous inflammation and fibrosis induced by Schistosoma japonicum associated with M2 macrophages in a mouse model

BACKGROUND: Potent granulomatous inflammation responses induced by schistosome eggs and resultant fibrosis are the primary causes of morbidity in schistosomiasis. Recombinant Sj16 (rSj16), a 16-kDa protein of Schistosoma japonicum produced in Escherichia coli, has been demonstrated to have novel imm...

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Detalles Bibliográficos
Autores principales:	Shen, Jia, Wang, Lifu, Peng, Mei, Liu, Zhen, Zhang, Beibei, Zhou, Tao, Sun, Xi, Wu, Zhongdao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755699/ https://www.ncbi.nlm.nih.gov/pubmed/31547847 http://dx.doi.org/10.1186/s13071-019-3697-z

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