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Modulation of osmotic stress-induced TRPV1 expression rescues human iPSC-derived retinal ganglion cells through PKA

BACKGROUND: Transient receptor potential vanilloid 1 (TRPV1), recognized as a hyperosmolarity sensor, is a crucial ion channel involved in the pathogenesis of neural and glial signaling. Recently, TRPV1 was determined to play a role in retinal physiology and visual transmission. In this study, we so...

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Detalles Bibliográficos
Autores principales:	Hsu, Chih-Chien, Chien, Ke-Hung, Yarmishyn, Aliaksandr A., Buddhakosai, Waradee, Wu, Wen-Ju, Lin, Tai-Chi, Chiou, Shih-Hwa, Chen, Jiann-Torng, Peng, Chi-Hsien, Hwang, De-Kuang, Chen, Shih-Jen, Chang, Yuh-Lih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755708/ https://www.ncbi.nlm.nih.gov/pubmed/31547874 http://dx.doi.org/10.1186/s13287-019-1363-1

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