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Functional analyses of ancestral thioredoxins provide insights into their evolutionary history

Thioredoxin (Trx) is a conserved, cytosolic reductase in all known organisms. The enzyme receives two electrons from NADPH via thioredoxin reductase (TrxR) and passes them on to multiple cellular reductases via disulfide exchange. Despite the ubiquity of thioredoxins in all taxa, little is known abo...

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Detalles Bibliográficos
Autores principales:	Napolitano, Silvia, Reber, Robin J., Rubini, Marina, Glockshuber, Rudi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6755812/ https://www.ncbi.nlm.nih.gov/pubmed/31366732 http://dx.doi.org/10.1074/jbc.RA119.009718

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